@Emil What is Alexa region? I cannot find such setting on my Alexa app.
Can you also make sure that if it is possible to integrate Alexa and Flic with Flic version 1 without using a hub?

Do you have any update for this issue? I tried many times and even tried slbickford's way but still received the same error message "This Device is not supported". I use Flic(NOT Flic 2) without a hub, but still supposed to be able to integrate it with Alexa? Also, my system language is Japanese, therefore device names sometimes include multibyte characters. Does this have something to do with this error? I checked the feedbacks of Flic skill from Japanese users and they seem to have the same problem too.
(Note that I use the apps on my Android phone, Android version 10.)